Filgotinib (Jyseleca)

Indications

Moderate-to-severely active UC in adults up to 74 years, with caution in patients over 75 years.

Contraindications

Do not use for patients with absolute lymphocyte count less than 0.5x109 cells/litre; absolute neutrophil count less than 1x109 cells/litre; haemoglobin less than 8 g/dL; serious infection (active); tuberculosis (active). Avoid in pregnancy or while breastfeeding. Caution in moderate or severe renal impairment; malignancy; predisposition to infection; risk factors for cardiovascular disease and venous thromboembolism; risk of viral reactivation Patients should receive all recommended vaccinations and be evaluated for tuberculosis and viral hepatitis before treatment. Risk of reduced fertility in male patients. | Potential side effects: Dizziness; increased risk of infection; nausea.

Preparations Available

Oral tablet

Quantity

Dose: 200mg once daily. Discontinue if no response after 22 weeks.

Sizes Available

100mg tablet (30), £863.10; 200mg tablet (30), £863.10

Price

100mg tablet (30), £863.10; 200mg tablet (30), £863.10

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